CT and MR findings of brain aspergillosis

Okafuji, Takashi; Yabuuchi, Hidetake; Nagatoshi, Yoshihisa; Hattanda, Youichi; Fukuya, Tatsuro

doi:10.1016/S0895-6111(03)00033-8

Next »Computerized Medical Imaging and Graphics
Volume 27, Issue 6 , Pages 489-492, November 2003

CT and MR findings of brain aspergillosis

Takashi Okafuji
- Department of Radiology, National Kyushu Cancer Center, 3-1-1 Notame, Minami-ku, Fukuoka 811-1395, Japan
- Corresponding author. Address: Department of Clinical Radiology, Graduate School of Medical Sciences, Kyushu University, 3-1-1 Maidashi, Higash-ku, Fukuoka 812-8582, Japan. Tel.: +81-92-642-5695; fax: +81-92-642-5708
Hidetake Yabuuchi
- Department of Radiology, National Kyushu Cancer Center, 3-1-1 Notame, Minami-ku, Fukuoka 811-1395, Japan
Yoshihisa Nagatoshi
- Department of Pediatrics, National Kyushu Cancer Center, 3-1-1 Notame, Minami-ku, Fukuoka 811-1395, Japan
Youichi Hattanda
- Department of Pathology, National Kyushu Cancer Center, 3-1-1 Notame, Minami-ku, Fukuoka 811-1395, Japan
Tatsuro Fukuya
- Department of Radiology, National Oita Hospital, 2-11-45 Yokota, Oita 870-0263, Japan

Received 20 August 2002; accepted 11 February 2003.

Abstract

CT and MR findings of a case of brain aspergillosis with histopathologic correlation are reported. On both CT and MR images, there were multiple lesions in the corticomedullary junction (CMJ) that appeared to disrupt the cortical sulci and that were not enhanced by intravenous contrast material. In most of these lesions, there were centrally located structures that were enhanced by intravenous contrast material and that appeared to be continuous from markedly enhanced adjacent dilated cortical vessels. Histopathologic examination of the autopsy specimen showed multiple hemorrhagic infarcts in the CMJ with remaining dilated cortical vessels that had been thrombosed by aspergillus hyphae.

Keywords: Aspergillosis, Immunocompromised, Brain, CT, Brain, MR