Computerized Medical Imaging and Graphics
Volume 32, Issue 1 , Pages 67-77 , January 2008

CT-perfusion imaging of the human brain: Advanced deconvolution analysis using circulant singular value decomposition

  • H.-J. Wittsack

      Affiliations

    • Institute of Diagnostic Radiology, University of Duesseldorf, Moorenstrasse 5, 40225 Duesseldorf, Germany
    • Brain Imaging Center West, Research Center Jülich, 52425 Jülich, Germany
    • Corresponding Author InformationCorresponding author at: Institute of Diagnostic Radiology, University of Duesseldorf, Moorenstrasse 5, D-40225 Duesseldorf, Germany. Tel.: +49 211 8117356; fax: +49 211 8116299.
    • ,
  • A.M. Wohlschläger

      Affiliations

    • Department of Neurology, Nuclear Medicine, Neuroradiology, TU Munich, Möhlstrasse 28, 81675 Munich, Germany
    • ,
  • E.K. Ritzl

      Affiliations

    • Department of Neurology, Johns Hopkins University, School of Medicine, 600 N. Wolfe Street, Baltimore, MD 21287, USA
    • ,
  • R. Kleiser

      Affiliations

    • Institute of Neuroradiology, UniversitätsSpital Zürich, Frauenklinikstrasse 10, 8091 Zürich, Switzerland
    • ,
  • M. Cohnen

      Affiliations

    • Institute of Diagnostic Radiology, University of Duesseldorf, Moorenstrasse 5, 40225 Duesseldorf, Germany
    • ,
  • R.J. Seitz

      Affiliations

    • Brain Imaging Center West, Research Center Jülich, 52425 Jülich, Germany
    • Department of Neurology, Universität Düsseldorf, Moorenstrasse 5, 40225 Düsseldorf, Germany
    • ,
  • U. Mödder

      Affiliations

    • Institute of Diagnostic Radiology, University of Duesseldorf, Moorenstrasse 5, 40225 Duesseldorf, Germany

Received 15 August 2006 ,Revised 24 September 2007 ,Accepted 25 September 2007.

References 

  1. Lev MH, Segal AZ, Farkas J, Hossain ST, Putman C, Hunter GJ, et al. Utility of perfusion-weighted CT imaging in acute middle cerebral artery stroke treated with intra-arterial thrombolysis: prediction of final infarct volume and clinical outcome. Stroke. 2001;32(9):2021–2028
  2. Koenig M, Klotz E, Luka B, Venderink DJ, Spittler JF, Heuser L. Perfusion CT of the brain: diagnostic approach for early detection of ischemic stroke. Radiology. 1998;209(1):85–93
  3. Mayer TE, Hamann GF, Baranczyk J, Rosengarten B, Klotz E, Wiesmann M, et al. Dynamic CT perfusion imaging of acute stroke. AJNR Am J Neuroradiol. 2000;21(8):1441–1449
  4. Sunshine JL, Tarr RW, Lanzieri CF, Landis DM, Selman WR, Lewin JS. Hyperacute stroke: ultrafast MR imaging to triage patients prior to therapy. Radiology. 1999;212(2):325–332
  5. Sorensen AG, Buonanno FS, Gonzalez RG, Schwamm LH, Lev MH, Huang-Hellinger FR, et al. Hyperacute stroke: evaluation with combined multisection diffusion-weighted and hemodynamically weighted echo-planar MR imaging. Radiology. 1996;199(2):391–401
  6. Butcher K, Parsons M, Baird T, Barber A, Donnan G, Desmond P, et al. Perfusion thresholds in acute stroke thrombolysis. Stroke. 2003;34:2159–2164
  7. Shih LC, Saver JL, Alger JR, Starkman S, Leary MC, Vinuela F, et al. Perfusion-weighted magnetic resonance imaging thresholds identifying core, irreversibly infarcted tissue. Stroke. 2003;34:1425–1430
  8. Fiebach JB, Schellinger PD, Gass A, Kucinski T, Siebler M, Villringer A, et al. Stroke magnetic resonance imaging is accurate in hyperacute intracerebral hemorrhage: a multicenter study on the validity of stroke imaging. Stroke. 2004;35:502–506
  9. Wittsack HJ, Ritzl A, Fink GR, Wenserski F, Siebler M, Seitz RJ, et al. MR imaging in acute stroke: diffusion-weighted and perfusion imaging parameters for predicting infarct size. Radiology. 2002;222(2):397–403
  10. Handschu R, Garling A, Heuschmann PU, Kolominsky-Rabas PL, Erbguth F, Neundorfer B. Acute stroke management in the local general hospital. Stroke. 2001;32(4):866–870
  11. Warach S, Dashe JF, Edelman RR. Clinical outcome in ischemic stroke predicted by early diffusion-weighted and perfusion magnetic resonance imaging: a preliminary analysis. J Cereb Blood Flow Metab. 1996;16(1):53–59
  12. Meier P, Zierler KL. On the theory of the indicator-dilution method for measurement of blood flow and volume. J Appl Physiol. 1954;6(12):731–744
  13. Axel L. Cerebral blood flow determination by rapid-sequence computed tomography. Radiology. 1980;137:679–686
  14. Axel L. Tissue mean transit time from dynamic computed tomography by a simple deconvolution technique. Invest Radiol. 1983;18:94–99
  15. Gobbel GT, Fike JR. A deconvolution method for evaluating indicator-dilution curves. Phys Med Biol. 1994;39(11):1833–1854
  16. Roland PE, Eriksson L, Stone-Elander S, Widen L. Does mental activity change the oxidative metabolism of the brain?. J Neurosci. 1987;7(8):2373–2389
  17. Herzog H, Seitz RJ, Tellmann L, Rota Kops E, Julicher F, Schlaug G. Quantitation of regional cerebral blood flow with 15O-butanol and positron emission tomography in humans. J Cereb Blood Flow Metab. 1996;16(4):645–649
  18. Huang SC, Phelps ME. Principles of tracer kinetic modeling in positron emission tomography and autoradiography. In:  Phelps ME,  Mazziotta JC,  Schelbert HR editor. Positron emission tomography and autoradiography. New York: Raven Press; 1986;p. 287–346
  19. Ostergaard L, Weisskoff RM, Chesler DA, Gyldensted C, Rosen BR. High resolution measurement of cerebral blood flow using intravascular tracer bolus passages. Part I. Mathematical approach and statistical analysis. Magn Reson Med. 1996;36(5):715–725
  20. Ostergaard L, Sorensen AG, Kwong KK, Weisskoff RM, Gyldensted C, Rosen RR. High resolution measurement of cerebral blood flow using intravascular tracer bolus passages. Part II. Experimental comparison and preliminary results. Magn Reson Med. 1996;36(5):726–736
  21. Eastwood JD, Lev MH, Azhari T, Lee TY, Barboriak DP, Delong DM, et al. CT perfusion scanning with deconvolution analysis: pilot study in patients with acute middle cerebral artery stroke. Radiology. 2002;222(1):227–236
  22. Cenic A, Nabavi DG, Craen RA, Gelb AW, Lee TY. Dynamic CT measurement of cerebral blood flow: a validation study. AJNR Am J Neuroradiol. 1999;20(1):63–73
  23. Calamante F, Gadian DG, Connelly A. Delay and dispersion effects in dynamic susceptibility contrast MRI: simulations using singular value decomposition. Magn Reson Med. 2000;44(3):466–473
  24. Ibaraki M, Shimosegawa E, Toyoshima H, Takahashi K, Miura S, Kanno I. Tracer delay correction of cerebral blood flow with dynamic susceptibility contrast-enhanced MRI. J Cereb Blood Flow Metab. 2005;25(3):378–390
  25. Rose SE, Janke AL, Griffin M, Strudwick MW, Finnigan S, Semple J, et al. Improving the prediction of final infarct size in acute stroke with bolus delay-corrected perfusion MRI measures. J Magn Reson Imaging. 2004;20(6):941–947
  26. Wu O, Ostergaard L, Weisskoff RM, Benner T, Rosen BR, Sorensen AG. Tracer arrival timing-insensitive technique for estimating flow in MR perfusion-weighted imaging using singular value decomposition with a block-circulant deconvolution matrix. Magn Reson Med. 2003;50(1):164–174
  27. Liu HL, Pu Y, Liu Y, Nickerson L, Andrews T, Fox PT, et al. Cerebral blood flow measurement by dynamic contrast MRI using singular value decomposition with an adaptive threshold. Magn Reson Med. 1999;42(1):167–172
  28. Press WH, Teukolsky SA, Vetterling WT, Flannery BP. Numerical recipes in C. The art of scientific computing. 2nd ed.. Oxford: Cambridge University Press; 1992;
  29. Leenders KL, Perani D, Lammertsma AA, Heather JD, Buckingham P, Healy MJ, et al. Cerebral blood flow, blood volume and oxygen utilization. Normal values and effect of age. Brain. 1990;113(1):27–47
  30. Reichenbach JR, Rother J, Jonetz-Mentzel L, Herzau M, Fiala A, Weiller C, et al. Acute stroke evaluated by time-to-peak mapping during initial and early follow-up perfusion CT studies. AJNR Am J Neuroradiol. 1999;20(10):1842–1850
  31. Eastwood JD, Provenzale JM, Hurwitz LM, Lee TY. Practical injection-rate CT perfusion imaging: deconvolution-derived hemodynamics in a case of stroke. Neuroradiology. 2001;43(3):223–226
  32. Eckstein HH, Ringleb P, Dorfler A, Klemm K, Muller BT, Zegelman M, et al. The carotid surgery for ischemic stroke trial: a prospective observational study on carotid endarterectomy in the early period after ischemic stroke. J Vasc Surg. 2002;36(5):997–1004
  33. Huber R, Muller BT, Seitz RJ, Siebler M, Modder U, Sandmann W. Carotid surgery in acute symptomatic patients. Eur J Vasc Endovasc Surg. 2003;25(1):60–67
  34. Kudo K, Terae S, Katho C, Oka M, Shiga T, Tamaki N, et al. Quantitative cerebral blood flow measurement with dynamic perfusion CT using the vascular-pixel elimination method: comparison with H215O positron emission tomography. Am J Neuroradiol. 2003;24:419–426

PII: S0895-6111(07)00137-1

doi: 10.1016/j.compmedimag.2007.09.004

Computerized Medical Imaging and Graphics
Volume 32, Issue 1 , Pages 67-77 , January 2008

Article Tools

* Image Usage & Resolution