Evaluation of required saline volume in dynamic contrast-enhanced computed tomography using saline flush technique
Received 30 June 2008; accepted 29 September 2008.
Abstract
The present study was performed to find the required volume of physiological saline for flushing that will allow the most efficient use of contrast medium during the early phase of dynamic CT. We calculated contrast medium aortic arrival time (AT), time to peak aortic enhancement (TPAE) and the elapsed time to TPAE from AT (rise time) from the TECs of pharmacokinetic analysis and clinical study. The rise time determined in the clinical study was 6.2s, which was shorter than that in the simulation study. In the present study, an appropriate volume for saline flush was estimated to be about 18ml.
aRadiological Center, University of Fukui Hospital, 23-3, Matsuokashimoaizuki, eiheiji-cho, Yoshida-gun, Fukui 910-1193, Japan
bDivision of Health Sciences, Kanazawa University Graduate School of Medicine Science, 5-11-80 Kodatsuno, Kanazawa, Ishikawa 920-0942, Japan
cDepartment of Radiology, Facility of Medical Sciences, University of Fukui, 23-3, Matsuokashimoaizuki, eiheiji-cho, Yoshida-gun, Fukui 910-1193, Japan
Corresponding author at: Radiological Center, University of Fukui Hospital, 23-3, Matsuokashimoaizuki, eiheiji-cho, Yoshida-gun, Fukui 910-1193, Japan. Tel.: +81 776 61 3111; fax: +81 776 61 8154.
ABSTRACT